Proteintech

RAB11FIP5 Polyclonal Antibody

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RAB11FIP5 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 14594-1-AP (RAB11FIP5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

14594-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 1 publication 1 publication
Immunocytochemistry (ICC/IF)	Assay-dependent	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RAB11FIP5 Fusion Protein Ag6128 (1-250 aa encoded by BC035013) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.13 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MALVRGAEP AAGPSRWLPT HVQVTVLRAR GLRGKSSGAG STSDAYTVIQ VGREKYSTSV VEKTHGCPEW REECSFELPP GALDGLLRAQ EADAGPAPWA ASSAAACELV LTTMHRSLIG VDKFLGQATV ALDEVFGAGR AQHTQWYKLH SKPGKKEKER GEIEVTIQFT RNNLSAMFDL SMKDKPRSPF SKIRDKMKGK KKYDLESASA ILPSSAIEDP DLGSLGKMGK AKGFFLRNKL RKSSLTQSNT S (1-250 aa encoded by BC035013)

Target Information

Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.

Nature communications

He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J

Fri Aug 17 00:00:00 EDT 2018

Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.

Nature communications

He K,Ma X,Xu T,Li Y,Hodge A,Zhang Q,Torline J,Huang Y,Zhao J,Ling K,Hu J

Fri Aug 17 00:00:00 EDT 2018

Bioinformatics

Protein Aliases: Gaf-1; Gamma-SNAP-associated factor 1; Phosphoprotein pp75; RAB11 family interacting protein 5 (class I); Rab11 family-interacting protein 5; Rab11-FIP5; Rab11-interacting protein Rip11

Gene Aliases: 9130206P09Rik; C75969; D6Ertd32e; GAF1; KIAA0857; pp75; RAB11FIP5; RIP11

UniProt ID: (Human) Q9BXF6, (Mouse) Q8R361

Entrez Gene ID: (Human) 26056, (Rat) 312502, (Mouse) 52055

Function(s)

insulin secretion involved in cellular response to glucose stimulus regulated exocytosis cellular response to acidic pH regulation of protein localization to cell surface transport protein transport negative regulation of adiponectin secretion

Process(es)

protein binding Rab GTPase binding gamma-tubulin binding