Proteintech

RAB22A Polyclonal Antibody

View all (6) RAB22A antibodies

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RAB22A Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human gliomas using 12125-1-AP (RAB22A antibody) at dilution of 1:100 (under 10x lens).

RAB22A Antibody in Western Blot (WB) — COLO 320 cells were subjected to SDS PAGE followed by western blot with 12125-1-AP (RAB22A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

RAB22A Antibody in Western Blot (WB) — BxPC-3 cells were subjected to SDS PAGE followed by western blot with 12125-1-AP (RAB22A antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

RAB22A Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 12125-1-AP (RAB22A antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

RAB22A Antibody in Western Blot (WB) — A375 cells were subjected to SDS PAGE followed by western blot with 12125-1-AP (RAB22A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

RAB22A Antibody in Immunoprecipitation (IP) — IP result of anti-RAB22A (IP:12125-1-AP, 4ug; Detection:12125-1-AP 1:300) with COLO 320 cells lysate 2560 ug.

Product Details

12125-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 8 publications 8 publications
Immunohistochemistry (IHC)	-	View 3 publications 3 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:500	-
Immunocytochemistry (ICC/IF)	-	View 2 publications 2 publications
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human
Published species	Dog, Hamster, Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RAB22A Fusion Protein Ag2769 (1-194 aa encoded by BC015710) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.27 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MALRELKVC LLGDTGVGKS SIVWRFVEDS FDPNINPTIG ASFMTKTVQY QNELHKFLIW DTAGQERFRA LAPMYYRGSA AAIIVYDITK EETFSTLKNW VKELRQHGPP NIVVAIAGNK CDLIDVREVM ERDAKDYADS IHAIFVETSA KNAININELF IEISRRIPST DANLPSGGKG FKLRRQPSEP KRSCC (1-194 aa encoded by BC015710)

Target Information

The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes.

EMBO reports

Shakya S,Sharma P,Bhatt AM,Jani RA,Delevoye C,Setty SR

Sat Dec 01 00:00:00 EST 2018

Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes.

EMBO reports

Shakya S,Sharma P,Bhatt AM,Jani RA,Delevoye C,Setty SR

Sat Dec 01 00:00:00 EST 2018

The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.

Clinical cancer research : an official journal of the American Association for Cancer Research

Yin Y,Yao S,Hu Y,Feng Y,Li M,Bian Z,Zhang J,Qin Y,Qi X,Zhou L,Fei B,Zou J,Hua D,Huang Z

Fri Dec 01 00:00:00 EST 2017

The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.

Clinical cancer research : an official journal of the American Association for Cancer Research

Yin Y,Yao S,Hu Y,Feng Y,Li M,Bian Z,Zhang J,Qin Y,Qi X,Zhou L,Fei B,Zou J,Hua D,Huang Z

Fri Dec 01 00:00:00 EST 2017

Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.

Molecular vision

Ahram DF,Cook AC,Kecova H,Grozdanic SD,Kuehn MH

Tue Sep 30 00:00:00 EDT 2014

Human liver cell trafficking mutants: characterization and whole exome sequencing.

PloS one

Yuan F,Snapp EL,Novikoff PM,Suadicani SO,Spray DC,Potvin B,Wolkoff AW,Stanley P

Mon Sep 29 00:00:00 EDT 2014

New target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion.

PloS one

Margue C,Philippidou D,Reinsbach SE,Schmitt M,Behrmann I,Kreis S

Sat Jun 07 00:00:00 EDT 2014

Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.

Virology

Yamasaki T,Baron GS,Suzuki A,Hasebe R,Horiuchi M

Sat Feb 01 00:00:00 EST 2014

A specific subset of RabGTPases controls cell surface exposure of MT1-MMP, extracellular matrix degradation and three-dimensional invasion of macrophages.

Journal of cell science

Wiesner C,El Azzouzi K,Linder S

Mon Jul 01 00:00:00 EDT 2013

Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer.

Oncology reports

Tanaka T,Arai M,Wu S,Kanda T,Miyauchi H,Imazeki F,Matsubara H,Yokosuka O

Tue Nov 01 00:00:00 EDT 2011

Rab22 controls NGF signaling and neurite outgrowth in PC12 cells.

Molecular biology of the cell

Wang L,Liang Z,Li G

Sat Oct 01 00:00:00 EDT 2011

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.

Traffic (Copenhagen, Denmark)

Seto S,Tsujimura K,Koide Y

Fri Apr 01 00:00:00 EDT 2011

Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis.

Molecular biology of the cell

Zhu H,Liang Z,Li G

Sun Nov 01 00:00:00 EDT 2009

Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis.

Molecular biology of the cell

Zhu H,Liang Z,Li G

Sun Nov 01 00:00:00 EDT 2009

Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis.

Molecular biology of the cell

Zhu H,Liang Z,Li G

Sun Nov 01 00:00:00 EDT 2009

Bioinformatics

Protein Aliases: GTP-binding protein RAB22A; MGC16770; Rab-22; Ras-related protein Rab-22A

Gene Aliases: RAB22; RAB22A

UniProt ID: (Human) Q9UL26

Entrez Gene ID: (Human) 57403

endocytosis endosome organization small GTPase mediated signal transduction protein transport regulation of vesicle size

Process(es)

GTPase activity protein binding GTP binding GDP binding