This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: EDLNVNEVFK YLAEKYLQKL KQQIAEDPEL THSSSNKIGV FNTSGGSHSG QNSGTLNGGD VINLRPNKQR TKK
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 23, also known as HSPC137, is a 237 amino acid member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. Rab 23 is believed to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. Mutations in the gene encoding Rab 23 may result in Carpenter syndrome, also known as ACPS2 (acrocephalopolysyndactyly type 2), a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp781H0695; MGC8900; OTTHUMP00000040021; RAB 23; RAB family small GTP binding protein RAB 23; Ras-related protein Rab-23; RP3-496N17.3
Gene Aliases: HSPC137; RAB23
UniProt ID: (Human) Q9ULC3
Entrez Gene ID: (Human) 51715