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|Tested species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminal region of rat RAB3A conjugated to KLH|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with human, mouse, Xenopus and non-human primate based on 100% sequence homology.
In Western blot, this antibody is specific for ~27 kDa Rab 3 protein.
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab 3€™s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C18A3.6; ras-related protein Rab-3A; Ras-related small GTP binding protein 3A