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Proteintech
RAB3A Polyclonal Antibody
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Product Details
15029-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAB3A Fusion Protein Ag1903 (1-220 aa encoded by BC011782)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Amount
55.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASATDSRY GQKESSDQNF DYMFKILIIG NSSVGKTSFL FRYADDSFTP AFVSTVGIDF KVKTIYRNDK RIKLQIWDTA GQERYRTITT AYYRGAMGFI LMYDITNEES FNAVQDWSTQ IKTYSWDNAQ VLLVGNKCDM EDERVVSSER GRQLADHLGF EFFEASAKDN INVKQTFERL VDVICEKMSE SLDTADPAVT GAKQGPQLSD QQVPPHQDCA C (1-220 aa encoded by BC011782)
Target Information
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related small GTP binding protein 3A; unnamed protein product
Gene Aliases: RAB3; RAB3A
UniProt ID: (Human) P20336, (Rat) P63012, (Mouse) P63011
Entrez Gene ID: (Human) 5864, (Rat) 25531, (Mouse) 19339
respiratory system process
intracellular protein transport
vesicle docking involved in exocytosis
mitochondrion organization
neuromuscular synaptic transmission
axonogenesis
metabolic process
protein secretion
post-embryonic development
synaptic vesicle exocytosis
synaptic vesicle maturation
regulation of exocytosis
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
Rab protein signal transduction
positive regulation of ATPase activity
synaptic vesicle recycling
regulation of short-term neuronal synaptic plasticity
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
protein localization to plasma membrane
positive regulation of regulated secretory pathway
plasma membrane repair
exocytosis
protein transport
calcium ion regulated exocytosis
insulin secretion
lysosome localization
constitutive secretory pathway
regulated exocytosis
positive regulation of exocytosis
synaptic vesicle transport
establishment of localization in cell
acrosomal vesicle exocytosis
evoked neurotransmitter secretion
synaptic vesicle clustering
regulation of presynaptic dense core granule exocytosis
regulation of plasma membrane repair
transport
small GTPase mediated signal transduction
regulation of long-term synaptic potentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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