Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
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Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related small GTP binding protein 3A
Gene Aliases: RAB3; RAB3A