Proteintech

RAB3A Polyclonal Antibody

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Datasheet

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Questions & Answers

Datasheet

Certificates

Protocols

Questions & Answers

Datasheet

Certificates

Protocols

Questions & Answers

Additional Information:

Antibody Testing Data (8)

RAB3A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 8

RAB3A Antibody (15029-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using (Product # 15029-1-AP) (RAB3A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

RAB3A Antibody in Immunoprecipitation (IP)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image RAB3A Polyclonal Antibody

Product Details

15029-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAB3A Fusion Protein Ag1903 (1-220 aa encoded by BC011782)

3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

55.5 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MASATDSRY GQKESSDQNF DYMFKILIIG NSSVGKTSFL FRYADDSFTP AFVSTVGIDF KVKTIYRNDK RIKLQIWDTA GQERYRTITT AYYRGAMGFI LMYDITNEES FNAVQDWSTQ IKTYSWDNAQ VLLVGNKCDM EDERVVSSER GRQLADHLGF EFFEASAKDN INVKQTFERL VDVICEKMSE SLDTADPAVT GAKQGPQLSD QQVPPHQDCA C (1-220 aa encoded by BC011782)

Target Information

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related small GTP binding protein 3A; unnamed protein product

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Gene Aliases: RAB3; SCA52

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UniProt ID: (Human) P20336, (Rat) P63012, (Mouse) P63011

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Entrez Gene ID: (Human) 5864, (Rat) 25531, (Mouse) 19339

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Function(s)

GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding protein binding, bridging GTP-dependent protein binding myosin V binding ATPase activator activity GDP-dissociation inhibitor binding ATPase binding

Process(es)

plasma membrane repair respiratory system process exocytosis mitochondrion organization neuromuscular synaptic transmission axonogenesis post-embryonic development regulation of synaptic vesicle priming regulation of dopamine secretion synaptic vesicle exocytosis synaptic vesicle maturation calcium ion regulated exocytosis regulation of exocytosis insulin secretion lung development regulation of synaptic vesicle fusion to presynaptic membrane lysosome localization Rab protein signal transduction synaptic vesicle recycling regulated exocytosis regulation of short-term neuronal synaptic plasticity synaptic vesicle transport maintenance of presynaptic active zone structure sensory perception of touch response to electrical stimulus acrosomal vesicle exocytosis evoked neurotransmitter secretion synaptic vesicle clustering regulation of presynaptic dense core granule exocytosis positive regulation of regulated secretory pathway regulation of plasma membrane repair regulation of synaptic vesicle exocytosis constitutive secretory pathway positive regulation of exocytosis regulation of long-term synaptic potentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAB3A Polyclonal Antibody

RAB3A Antibody (15029-1-AP) in IHC (P)

Product Details

15029-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Amount

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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