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RAB3A Polyclonal Antibody
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Product Details
OSR00336W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 2-50 of mouse RAB3A conjugated to blue carrier protein has been used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous for RAB3B, C, D in human and rat.
Specificity of this antibody: RAB3.
Target Information
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related small GTP binding protein 3A; unnamed protein product
Gene Aliases: RAB3; RAB3A
UniProt ID: (Human) P20336, (Rat) P63012, (Mouse) P63011
Entrez Gene ID: (Human) 5864, (Rat) 25531, (Mouse) 19339
respiratory system process
intracellular protein transport
vesicle docking involved in exocytosis
mitochondrion organization
neuromuscular synaptic transmission
axonogenesis
metabolic process
protein secretion
post-embryonic development
synaptic vesicle exocytosis
synaptic vesicle maturation
regulation of exocytosis
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
Rab protein signal transduction
positive regulation of ATPase activity
synaptic vesicle recycling
regulation of short-term neuronal synaptic plasticity
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
protein localization to plasma membrane
positive regulation of regulated secretory pathway
plasma membrane repair
exocytosis
protein transport
calcium ion regulated exocytosis
insulin secretion
lysosome localization
constitutive secretory pathway
regulated exocytosis
positive regulation of exocytosis
synaptic vesicle transport
establishment of localization in cell
acrosomal vesicle exocytosis
evoked neurotransmitter secretion
synaptic vesicle clustering
regulation of presynaptic dense core granule exocytosis
regulation of plasma membrane repair
transport
small GTPase mediated signal transduction
regulation of long-term synaptic potentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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