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Proteintech
RAB3D Polyclonal Antibody
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Product Details
12320-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Dog,
Goat,
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAB3D Fusion Protein Ag2973 (1-219 aa encoded by BC016471)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
73.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASAGDTQA GPRDAADQNF DYMFKLLLIG NSSVGKTSFL FRYADDSFTP AFVSTVGIDF KVKTVYRHDK RIKLQIWDTA GQERYRTITT AYYRGAMGFL LMYDIANQES FAAVQDWATQ IKTYSWDNAQ VILVGNKCDL EDERVVPAED GRRLADDLGF EFFEASAKEN INVKQVFERL VDVICEKMNE SLEPSSSSGS NGKGPAVGDA PAPQPSSCSC (1-219 aa encoded by BC016471)
Target Information
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; glioblastoma overexpressed; GTP-binding protein Rab-3D; Rab3D upregulated with myeloid differentiation; Ras-related protein Rab-3D; unnamed protein product
Gene Aliases: C130057E11Rik; D2-2; GOV; RAB16; RAB3D; RAD3D
UniProt ID: (Human) O95716, (Mouse) P35276, (Rat) Q63942
Entrez Gene ID: (Human) 9545, (Mouse) 19340, (Rat) 140665
exocytosis
protein transport
regulation of exocytosis
bone resorption
positive regulation of regulated secretory pathway
transport
intracellular protein transport
vesicle docking involved in exocytosis
small GTPase mediated signal transduction
protein secretion
synaptic vesicle exocytosis
peptidyl-cysteine methylation
Rab protein signal transduction
protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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