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Proteintech
RAB3IP/Rabin8 Polyclonal Antibody
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Product Details
12321-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Dog,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAB3IP/Rabin8 Fusion Protein Ag2974 (21-254 aa encoded by BC015548)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Amount
43.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GKIDVLQAE VAALKTLVLS SSPTSPTQEP LPGGKTPFKK GHTRNKSTSS AMSGSHQDLS VIQPIVKDCK EADLSLYNEF RLWKDEPTMD RTCPFLDKIY QEDIFPCLTF SKSELASAVL EAVENNTLSI EPVGLQPIRF VKASAVECGG PKKCALTGQS KSCKHRIKLG DSSNYYYISP FCRYRITSVC NFFTYIRYIQ QGLVKQQDVD QMFWEVMQLR KEMSLAKLGY FKEEL (21-254 aa encoded by B C015548)
Target Information
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GAS64; gene trap PAT 12; Rab-3A-interacting protein; RAB3A-interacting protein; rab3ip; rab3ip {ECO:0000250|UniProtKB:Q96QF0}; rabin 3; Rabin-3; Rabin8; SSX2 interacting protein; SSX2-interacting protein; unnamed protein product
Gene Aliases: B230311A06; Gtpat12; RAB3IP; RABIN3; RABIN8
UniProt ID: (Human) Q96QF0, (Rat) Q62739, (Mouse) Q68EF0
Entrez Gene ID: (Human) 117177, (Rat) 29885, (Mouse) 216363
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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