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Proteintech
RAB3IP/Rabin8 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
29818-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAB3IP/Rabin8 fusion protein Ag31291
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
500 µg/mL
Amount
75 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: LPGGKTPFKK GHTRNKSTSS AMSGSHQDLS VIQPIVKDCK EADLSLYNEF RLWKDEPTMD RTCPFLDKIY QEDIFPCLTF SKSELASAVL EAVENNTLSI EPVGLQPIRF VKASAVECGG PKKCALTGQS KSCKHRIKLG DSS
Target Information
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAS64; rab3A-interacting protein; rabin-3; SSX2 interacting protein; unnamed protein product
Gene Aliases: RABIN3; RABIN8
UniProt ID: (Human) Q96QF0
Entrez Gene ID: (Human) 117177
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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