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          • Primary Antibodies ›
          • RAB3IP Antibodies

          Proteintech

          RAB3IP/Rabin8 Polyclonal Antibody

          View all (26) RAB3IP antibodies

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          Cite RAB3IP/Rabin8 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          RAB3IP/Rabin8 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          RAB3IP/Rabin8 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          RAB3IP/Rabin8 Antibody (29818-1-AP) in WB

          Human brain tissue was subjected to SDS PAGE followed by western blot with 29927-1-AP (RAB12 antibody) at dilution of 1:2,000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAB3IP/Rabin8 Antibody in Western Blot (WB)
          RAB3IP/Rabin8 Polyclonal Antibody

          Product Details

          29818-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          RAB3IP/Rabin8 fusion protein Ag31291
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          500 µg/mL

          Amount

          75 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Sequence of this protein is as follows: LPGGKTPFKK GHTRNKSTSS AMSGSHQDLS VIQPIVKDCK EADLSLYNEF RLWKDEPTMD RTCPFLDKIY QEDIFPCLTF SKSELASAVL EAVENNTLSI EPVGLQPIRF VKASAVECGG PKKCALTGQS KSCKHRIKLG DSS

          Target Information

          Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: GAS64; Rab-3A-interacting protein; Rab3A-interacting protein; Rabin-3; Rabin8; SSX2 interacting protein; SSX2-interacting protein; unnamed protein product

          View more View less

          Gene Aliases: RAB3IP; RABIN3; RABIN8

          View more View less

          UniProt ID: (Human) Q96QF0

          View more View less

          Entrez Gene ID: (Human) 117177

          View more View less

          Function(s)
          guanyl-nucleotide exchange factor activity protein binding identical protein binding GTPase binding
          Process(es)
          protein targeting to membrane Golgi to plasma membrane transport protein transport negative regulation of filopodium assembly cilium morphogenesis ciliary basal body-plasma membrane docking
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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