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Invitrogen
RAB3a Polyclonal Antibody
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Product Details
PA5149711
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RAB3A
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RIKLQIWDTA GQERYRTITT AYYRGAMGFI LMYDITNEES FNAVQDWSTQ IKTYSWDNAQ VLLVGNKCDM EDERVVSSER GRQLADHLGF EFFEASAKDN INVKQTFERL VDVICEKMSE SLDTADPAVT GAKQGPQLSD QQV
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C18A3.6; RAS-associated protein RAB3A; Ras-related protein Rab-3A; unnamed protein product
Gene Aliases: RAB3A
UniProt ID: (Human) P20336
Entrez Gene ID: (Human) 5864
plasma membrane repair
respiratory system process
exocytosis
mitochondrion organization
neuromuscular synaptic transmission
axonogenesis
post-embryonic development
protein transport
synaptic vesicle exocytosis
synaptic vesicle maturation
calcium ion regulated exocytosis
regulation of exocytosis
insulin secretion
lung development
regulation of synaptic vesicle fusion to presynaptic membrane
lysosome localization
synaptic vesicle recycling
constitutive secretory pathway
regulated exocytosis
positive regulation of exocytosis
regulation of short-term neuronal synaptic plasticity
synaptic vesicle transport
maintenance of presynaptic active zone structure
sensory perception of touch
response to electrical stimulus
establishment of localization in cell
acrosomal vesicle exocytosis
evoked neurotransmitter secretion
synaptic vesicle clustering
regulation of presynaptic dense core granule exocytosis
positive regulation of regulated secretory pathway
regulation of plasma membrane repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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