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Proteintech
RAB6A Polyclonal Antibody
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FIGURE: 1 / 7
RAB6A Antibody (10187-2-AP) in ICC/IF
Immunofluorescent analysis of (4% PFA) fixed HeLa cells using (Product # 10187-2-AP) RAB6A antibody, at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). F-actin is stained using CL555-phalloidin (red) and DNA is stained by DAPI (blue).
Product Details
10187-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAB6A Fusion Protein Ag0240 (1-208 aa encoded by BC003617)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSTGGDFGN PLRKFKLVFL GEQSVGKTSL ITRFMYDSFD NTYQATIGID FLSKTMYLED RTIRLQLWDT AGQERFRSLI PSYIRDSAAA VVVYDITNVN SFQQTTKWID DVRTERGSDV IIMLVGNKTD LADKRQVSIE EGERKAKELN VMFIETSAKA GYNVKQLFRR VAAALPGMES TQDRSREDMI DIKLEKPQEQ PVSEGGCSC (1-208 aa encoded by BC003617 )
Target Information
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it regulates retrograde transport from the late endosomes via the Golgi to endoplasmic reticulum (ER) pathway. Three isoforms exist due to alternative splicing events, namely the ubiquitously expressed isoforms Rab 6A' and Rab 6A, and the brain-specific isoform Rab 6B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GTPase; Rab GTPase; Rab-6; RAB6, member RAS oncogene family; RAB6A; RAB6A'; RAB6B, member RAS oncogene family; Ras-related protein Rab-6A; transporter; unnamed protein product
Gene Aliases: 2610028L11Rik; AA419671; MNCb-1660; RAB6; RAB6A; Rab6b; RCO4-3
UniProt ID: (Human) P20340, (Rat) Q9WVB1, (Mouse) P35279
Entrez Gene ID: (Human) 5870, (Rat) 84379, (Mouse) 19346
protein targeting to Golgi
intracellular protein transport
retrograde vesicle-mediated transport, Golgi to ER
intra-Golgi vesicle-mediated transport
metabolic process
peptidyl-cysteine methylation
antigen processing and presentation
Rab protein signal transduction
positive regulation of ATPase activity
protein localization to Golgi apparatus
early endosome to Golgi transport
retrograde transport, endosome to Golgi
Golgi vesicle transport
transport
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
neuron projection development
minus-end-directed organelle transport along microtubule
protein localization to Golgi membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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