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Proteintech
RAB8B Polyclonal Antibody
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Product Details
55295-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to RABB8B.
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ38125; GTPase Rab8b; RAB-8b protein; RAB44, member RAS oncogene family; Ras-related protein Rab-8B; unnamed protein product
Gene Aliases: 5930437D16; D330025I23Rik; RAB8B
UniProt ID: (Human) Q92930, (Rat) P70550, (Mouse) P61028
Entrez Gene ID: (Human) 51762, (Rat) 266688, (Mouse) 235442
exocytosis
protein transport
antigen processing and presentation
positive regulation of cell projection organization
endocytic recycling
protein import into peroxisome membrane
positive regulation of corticotropin secretion
cilium morphogenesis
cell-substrate junction organization
intracellular protein transport
vesicle docking involved in exocytosis
metabolic process
protein secretion
synaptic vesicle exocytosis
regulation of exocytosis
Rab protein signal transduction
cellular response to insulin stimulus
adherens junction organization
cilium assembly
Golgi vesicle fusion to target membrane
protein localization to plasma membrane
transport
small GTPase mediated signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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