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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 830-1069 of human RABGAP1 (NP_036329.3). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.55 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2855674 |
Sequence of this protein is as follows: QQEDPIERFE RENRRLQEAN MRLEQENDDL AHELVTSKIA LRKDLDNAEE KADALNKELL MTKQKLIDAE EEKRRLEEES AQLKEMCRRE LDKAESEIKK NSSIIGDYKQ ICSQLSERLE KQQTANKVEI EKIRQKVDDC ERCREFFNKE GRVKGISSTK EVLDEDTDEE KETLKNQLRE MELELAQTKL QLVEAECKIQ DLEHHLGLAL NEVQAAKKTW FNRTLSSIKT ATGVQGKETC
RABGAP1 may act as a GTPase-activating protein of RAB6A and play a role in microtubule nucleation by centrosome. It may participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GAP and centrosome-associated protein; Rab GTPase-activating protein 1; rab6 GTPase activating protein (GAP and centrosome-associated); Rab6 GTPase activating protein, GAPCenA; Rab6 GTPase-activating protein GAPCenA; rabgap1; RP11-123N4.2; TBC1 domain family, member 11
Gene Aliases: GAPCENA; HSPC094; Kiaa4104; mKIAA4104; RABGAP1; TBC1D11
UniProt ID: (Human) Q9Y3P9, (Mouse) A2AWA9
Entrez Gene ID: (Human) 23637, (Mouse) 227800
Molecular Function:
G-protein modulator
protein-binding activity modulator
GTPase-activating protein
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