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Product Details
PA5-30484
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:5,000-1:20,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fragment corresponding to a region within amino acids 720 and 1058 of Human RABGAP1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.83 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
0.1M tris glycine, pH 7, with 20% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2547958 |
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, mouse brain.
Predicted reactivity: Mouse (96%), Rat (95%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RABGAP1 may act as a GTPase-activating protein of RAB6A and play a role in microtubule nucleation by centrosome. It may participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAP and centrosome-associated protein; Rab GTPase-activating protein 1; rab6 GTPase activating protein (GAP and centrosome-associated); Rab6 GTPase activating protein, GAPCenA; Rab6 GTPase-activating protein GAPCenA; rabgap1; RP11-123N4.2; TBC1 domain family, member 11
Gene Aliases: GAPCENA; HSPC094; Kiaa4104; mKIAA4104; RABGAP1; TBC1D11
UniProt ID: (Human) Q9Y3P9, (Mouse) A2AWA9
Entrez Gene ID: (Human) 23637, (Mouse) 227800
Molecular Function:
G-protein modulator
protein-binding activity modulator
GTPase-activating protein
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