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          • Primary Antibodies ›
          • RAC1/2 Antibodies

          Osenses

          RAC1, RAC2 Polyclonal Antibody

          1 Reference

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          Cite RAC1, RAC2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          RAC1, RAC2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          RAC1, RAC2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          RAC1, RAC2 Antibody (OSR00269W-100UL) in WB

          WB on tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody dilution: 1:1000 incubated overnight at 4°C.. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAC1, RAC2 Antibody in Western Blot (WB)
          RAC1, RAC2 Polyclonal Antibody

          Product Details

          OSR00269W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:2,000
          -

          Immunohistochemistry (IHC)

          1:1,000-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from aa region 100-150 of of human RAC1 conjugated to blue carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          The peptide is homologous in rat, mouse, guinea pig, bovine, xenopus, dog, zebrafish and chicken.

          Specificity of this antibody: RAC1 and RAC2.

          Target Information

          The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Cell migration-inducing gene 5 protein; EN-7 protein; GX; p21-Rac1; p21-Rac2; Protein EN-7; Rac1ins; RAC2; ras-like protein; Ras-like protein TC25; RAS-related C3 botulinum substrate 2; ras-related C3 botulinum toxin substrate; Ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac1; Small G protein; unnamed protein product

          View more View less

          Gene Aliases: AI323801; AI452260; AL023026; D5Ertd559e; EN-7; Gx; HSPC022; IMD73A; IMD73B; IMD73C; MIG5; MRD48; p21-Rac1; p21-Rac2; Rac; Rac-1; RAC1; RAC2; TC-25; TC25

          View more View less

          UniProt ID: (Human) P63000, (Human) P15153, (Mouse) P63001, (Rat) Q6RUV5, (Mouse) Q05144

          View more View less

          Entrez Gene ID: (Human) 5879, (Human) 5880, (Mouse) 19353, (Rat) 363875, (Rat) 366957, (Mouse) 19354

          View more View less

          Function(s)
          nucleotide binding GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding hydrolase activity enzyme binding protein kinase binding GTP-dependent protein binding thioesterase binding macromolecular complex binding Rho GDP-dissociation inhibitor binding protein kinase regulator activity Rab GTPase binding histone deacetylase binding small GTPase immunoglobulin
          Process(es)
          neuron migration positive regulation of protein phosphorylation auditory receptor cell morphogenesis sphingosine-1-phosphate signaling pathway epithelial cell morphogenesis endocytosis phagocytosis, engulfment inflammatory response hyperosmotic response cytoskeleton organization actin filament organization cell adhesion cell-matrix adhesion establishment or maintenance of cell polarity enzyme linked receptor protein signaling pathway G-protein coupled receptor signaling pathway small GTPase mediated signal transduction axon guidance motor neuron axon guidance regulation of cell shape response to wounding anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process regulation of lamellipodium assembly positive regulation of lamellipodium assembly positive regulation of endothelial cell migration regulation of fibroblast migration negative regulation of fibroblast migration regulation of cell-substrate adhesion positive regulation of cell-substrate adhesion regulation of neuron maturation dendrite development cell migration Rac protein signal transduction cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration cerebral cortex GABAergic interneuron development regulation of cell morphogenesis cell projection assembly lamellipodium assembly actin cytoskeleton organization actin filament polymerization regulation of cell migration positive regulation of actin filament polymerization cortical cytoskeleton organization forebrain development positive regulation of microtubule polymerization ruffle organization response to lipopolysaccharide negative regulation of interleukin-23 production regulation of actin cytoskeleton organization substrate adhesion-dependent cell spreading positive regulation of Rho protein signal transduction intracellular signal transduction non-canonical Wnt signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus superoxide anion generation erythrocyte enucleation engulfment of apoptotic cell cell-cell junction organization regulation of nitric oxide biosynthetic process respiratory burst regulation of JAK-STAT cascade hepatocyte growth factor receptor signaling pathway regulation of neuronal synaptic plasticity negative regulation of receptor-mediated endocytosis anatomical structure arrangement neuron projection morphogenesis dendrite morphogenesis cell motility homeostasis of number of cells within a tissue regulation of stress fiber assembly positive regulation of stress fiber assembly localization within membrane positive regulation of focal adhesion assembly positive regulation of protein kinase B signaling synaptic transmission, GABAergic Wnt signaling pathway, planar cell polarity pathway regulation of respiratory burst cell chemotaxis positive regulation of dendritic spine development regulation of cell adhesion involved in heart morphogenesis regulation of ERK5 cascade semaphorin-plexin signaling pathway dopaminergic neuron differentiation protein localization to plasma membrane angiotensin-activated signaling pathway involved in heart process positive regulation of neutrophil chemotaxis cochlea morphogenesis ruffle assembly regulation of postsynapse assembly positive regulation of substrate adhesion-dependent cell spreading positive regulation of ruffle assembly regulation of synaptic vesicle endocytosis regulation of neutrophil migration positive regulation of bicellular tight junction assembly positive regulation of skeletal muscle acetylcholine-gated channel clustering interneuron migration midbrain dopaminergic neuron differentiation positive regulation of ovarian follicle development regulation of neuron migration chemotaxis signal transduction cell proliferation regulation of T cell proliferation regulation of mast cell degranulation bone resorption regulation of mast cell chemotaxis mast cell proliferation positive regulation of mast cell proliferation lymphocyte aggregation positive regulation of protein targeting to mitochondrion mast cell chemotaxis metabolic process positive regulation of phosphatidylinositol 3-kinase activity positive regulation of DNA replication cellular response to mechanical stimulus positive regulation of cell proliferation
          It has to be done as per old AB suggested Products section.

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