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Invitrogen
RAC1/RAC2/RAC3 Recombinant Rabbit Monoclonal Antibody (K01_4T53)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA567776
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_4T53
Immunogen
A synthesized peptide derived from human Rac1/2/3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol, 150mM NaCl, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell migration-inducing gene 5 protein; EN-7 protein; GX; p21-Rac1; p21-Rac2; p21-Rac3; Protein EN-7; Ras-like protein TC25; RAS-related C3 botulinum substrate 2; Ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); Ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); rho family, small GTP binding protein Rac1; Small G protein
Gene Aliases: AI323801; AI452260; AL023026; D5Ertd559e; MIG5; Rac; RAC1; Rac1B; RAC2; RAC3; TC25
UniProt ID: (Mouse) P63001, (Rat) Q6RUV5, (Mouse) Q05144, (Mouse) P60764
Entrez Gene ID: (Mouse) 19353, (Rat) 363875, (Rat) 366957, (Mouse) 19354, (Mouse) 170758, (Rat) 688319
positive regulation of protein phosphorylation
auditory receptor cell morphogenesis
mast cell chemotaxis
epithelial cell morphogenesis
endocytosis
phagocytosis, engulfment
chemotaxis
hyperosmotic response
cytoskeleton organization
actin filament organization
cell adhesion
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
axon guidance
metabolic process
cell proliferation
positive regulation of lamellipodium assembly
regulation of fibroblast migration
positive regulation of cell-substrate adhesion
regulation of neuron maturation
dendrite development
cell migration
cerebral cortex radially oriented cell migration
embryonic olfactory bulb interneuron precursor migration
cerebral cortex GABAergic interneuron development
regulation of cell morphogenesis
lamellipodium assembly
actin cytoskeleton organization
actin filament polymerization
regulation of cell migration
positive regulation of actin filament polymerization
ruffle organization
negative regulation of interleukin-23 production
substrate adhesion-dependent cell spreading
positive regulation of phosphatidylinositol 3-kinase activity
engulfment of apoptotic cell
cell-cell junction organization
bone resorption
positive regulation of DNA replication
anatomical structure arrangement
dendrite morphogenesis
cell motility
homeostasis of number of cells within a tissue
positive regulation of stress fiber assembly
localization within membrane
positive regulation of focal adhesion assembly
synaptic transmission, GABAergic
Wnt signaling pathway, planar cell polarity pathway
regulation of respiratory burst
cellular response to mechanical stimulus
semaphorin-plexin signaling pathway
dopaminergic neuron differentiation
protein localization to plasma membrane
positive regulation of neutrophil chemotaxis
cochlea morphogenesis
ruffle assembly
positive regulation of substrate adhesion-dependent cell spreading
Rac protein signal transduction
positive regulation of cell proliferation
regulation of cell-substrate adhesion
cell projection assembly
lymphocyte aggregation
regulation of neutrophil migration
positive regulation of protein targeting to mitochondrion
neuron projection development
positive regulation of cell adhesion mediated by integrin
neuromuscular process controlling balance
neuromuscular process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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