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Invitrogen
RAC3 Polyclonal Antibody
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Product Details
PA5-144214
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Ras-related C3 botulinum toxin substrate 3 protein (1-192AA)
Conjugate
Form
Liquid
Concentration
0.68 mg/mL
Amount
68 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTMUSP00000004488; p21 Rac3; p21-Rac3; Rac1B; RAC3; RAC3_HUMAN; RAS related C3 botulinum substrate 3; Ras related C3 botulinum toxin substrate 3; Ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Rho family small GTP binding protein Rac3; rho family, small GTP binding protein Rac3; RP23-84C12.18
Gene Aliases: RAC3
UniProt ID: (Human) P60763
Entrez Gene ID: (Human) 5881
actin filament organization
establishment or maintenance of cell polarity
small GTPase mediated signal transduction
motor neuron axon guidance
regulation of cell shape
regulation of cell-substrate adhesion
regulation of neuron maturation
Wnt signaling pathway
Rac protein signal transduction
cerebral cortex GABAergic interneuron development
regulation of cell morphogenesis
cell projection assembly
actin cytoskeleton organization
cortical cytoskeleton organization
neuron projection development
regulation of actin cytoskeleton organization
positive regulation of cell adhesion mediated by integrin
intracellular signal transduction
respiratory burst
homeostasis of number of cells within a tissue
neuromuscular process controlling balance
neuromuscular process
synaptic transmission, GABAergic
cell chemotaxis
postsynaptic actin cytoskeleton organization
regulation of postsynapse assembly
positive regulation of substrate adhesion-dependent cell spreading
regulation of neutrophil migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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