Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Positive test controls include: Jurkat, Mouse thymus, C6.
Immunogen sequence: VDPVEPMPTM TDQTTLVPNE EEAFALEPID ITVKETKAKR KRKLIVDSVK ELDSKTIRAQ LSDYSDIVTT LDLAPPTKKL MMWKETGGVE KLFSLPAQPL WNNRLLKLFT RCLTPLVPED LRKRRKGGEA DNLDEFLKEF
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Double-strand-break repair protein rad21 homolog; FLJ25655; FLJ40596; h NXP-1; hHR21; KIAA0078RAD21; kleisin; mHR21; Nuclear matrix protein 1; NXP-1; Pokeweed agglutinin-binding protein 29; protein involved in DNA double-strand break repair; PW29; RAD21 homolog; SCC1 homolog; sister chromatid cohesion 1
Gene Aliases: CDLS4; hHR21; HR21; HRAD21; KIAA0078; MCD1; mKIAA0078; NXP1; RAD21; SCC1
UniProt ID: (Human) O60216, (Mouse) Q61550
Entrez Gene ID: (Human) 5885, (Rat) 314949, (Mouse) 19357
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