This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 14
Recommended positive controls: K562, THP-1, HL-60, NIH-3T3, JC, BCL-1.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (90%), Chicken (94%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
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Protein Aliases: 64-kDa C-terminal product; 64-kDa carboxy-terminal product; 65-kDa carboxy-terminal product; Double-strand-break repair protein rad21 homolog; FLJ25655; FLJ40596; h NXP-1; hHR21; KIAA0078RAD21; kleisin; mHR21; Nuclear matrix protein 1; NXP-1; Pokeweed agglutinin-binding protein 29; protein involved in DNA double-strand break repair; PW29; RAD21 homolog; SCC1 homolog; sister chromatid cohesion 1
Gene Aliases: CDLS4; hHR21; HR21; HRAD21; KIAA0078; MCD1; mKIAA0078; NXP1; RAD21; SCC1