Recommended positive controls: Yeast.
Predicted reactivity: Yeast (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: 153 kDa protein; DNA repair protein RAD50; hsRAD50; MRX complex DNA-binding subunit; RAD50 2; RAD50 PEN; RAD50-2; RAD50-3
Gene Aliases: N0872; RAD50; YNL250W
UniProt ID: (Baker's yeast) P12753
Entrez Gene ID: (Baker's yeast) 855471