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|Tested species reactivity||Yeast|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 644 and 989 of Yeast RAD50|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-32176 targets RAD50 in WB applications and shows reactivity with Yeast samples.
The PA5-32176 immunogen is recombinant fragment corresponding to a region within amino acids 644 and 989 of Yeast RAD50.
Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific exonuclease activity. Rad50 provides ATP-dependent control of mre11 by unwinding and/or repositioning DNA ends into the mre11 active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
153 kDa protein; DNA repair protein RAD50; Rad50p
N0872; RAD50; YNL250W