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Positive Samples: NIH3T3, MCF-7, A-549, HT-29, Mouse lung; Cellular Location: Chromosome, Nucleus, telomere
Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA repair protein RAD50; hRAD50; hsRAD50; mRad50; RAD50 2; RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD50-2; RAD50-3
Gene Aliases: hRad50; Mrell; NBSLD; RAD50; RAD502; Rad50l
UniProt ID: (Human) Q92878
Entrez Gene ID: (Human) 10111, (Mouse) 19360
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