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Invitrogen
RAD51 Polyclonal Antibody
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Product Details
PA5-34905
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Yeast
Published species
C. elegans,
Yeast
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of Saccharomyces cerevisiae S288c Rad51. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: yeast.
Predicted reactivity: Yeast (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA repair protein RAD51
Gene Aliases: MUT5; RAD51; YER095W
UniProt ID: (Baker's yeast) P25454
Entrez Gene ID: (Baker's yeast) 856831
meiotic joint molecule formation
telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA recombinase assembly
DNA metabolic process
DNA repair
nucleotide-excision repair
double-strand break repair
DNA recombination
mitotic recombination
cellular response to DNA damage stimulus
reciprocal meiotic recombination
heteroduplex formation
strand invasion
mitochondrial DNA repair
chromosome organization involved in meiotic cell cycle
mitotic recombination-dependent replication fork processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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