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|Tested species reactivity||Yeast|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 259 of RAD51 (Uniprot ID#P25454)|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34905 targets RAD51 in WB applications and shows reactivity with Yeast samples.
The PA5-34905 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 259 of RAD51 (Uniprot ID#P25454).
Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogenes and tumor suppressors such as BRACA1, BRACA2, and P53 for the maintenance of genome stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BRCA1/BRCA2-containing complex; DNA repair protein RAD51; E. coli; homolog of; RecA; RecA-like protein; recombinase RAD51; recombination protein A; subunit 5
MUT5; RAD51; YER095W