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RAD54 Polyclonal Antibody
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Product Details
600-401-684
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a N-Terminal region near aa 1-25 of Human RAD54 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
BLAST analysis indicates 100 % homology of the immunizing sequence with RAD54 from human. Cross reactivity with RAD54 protein homologues from other sources may not occur as sequence homology varies by at least one amino acid residue in this sequence.
Target Information
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATR2; DNA repair and recombination protein RAD54-like; h hRAD54; hHR54; MGC2094; MRXHF1; RAD54; RAD54 homolog; RP5-875J14.1; SFM1; SHS; unnamed protein product; XH2; XNP; ZNF-HX
Gene Aliases: hHR54; HR54; hRAD54; RAD54A; RAD54L
UniProt ID: (Human) Q92698
Entrez Gene ID: (Human) 8438
double-strand break repair via homologous recombination
DNA repair
double-strand break repair
DNA recombination
cellular response to DNA damage stimulus
reciprocal meiotic recombination
determination of adult lifespan
response to xenobiotic stimulus
response to ionizing radiation
double-strand break repair via synthesis-dependent strand annealing
chromosome organization
meiotic cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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