Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human RAG1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.62 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2805070 |
Immunogen sequence: MAASFPPTLG LSSAPDEIQH PHIKFSEWKF KLFRVRSFEK TPEEAQKEKK DSFEGKPSLE QSPAVLDKAD GQKPVPTQPL LKAHPKFSKK FHDNEKARGK AIHQANLRHL CRICGNSFRA DEHNRRYPVH GPVDGKTLGL LRKKEKRATS WPDLIAKVFR IDVKADVDSI HPTEFCHNCW SIMHRKFSSA PCEVYFPRNV TMEWHPHTPS CDICNTARRG LKRKSLQPNL QLSKKLKTVL DQARQARQRK RRAQARISSK DVMKKIANCS; Positive Samples: Mouse thymus; Cellular Location: Nucleus
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase RAG1; Endonuclease RAG1; MGC43321; RAG-1; RAG-1 Antibody; recombinase activating gene 1; recombination activating gene 1 Antibody; recombination activating protein 1; recombination-activating gene 1; RING finger protein 74; RING-type E3 ubiquitin transferase RAG1; RNF74 Antibody; V(D)J recombination-activating protein 1
Gene Aliases: RAG-1; RAG1; RNF74
UniProt ID: (Human) P15918, (Mouse) P15919
Entrez Gene ID: (Human) 5896, (Mouse) 19373
Molecular Function:
DNA metabolism protein
endodeoxyribonuclease
nucleic acid metabolism protein
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