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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, corresponding to amino acids 99-117 of Human RAIDD.|
|Contains||0.02% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30806 detects RAIDD from human samples.
PA1-30806 has been successfully used in Western blot applications.
The PA1-30806 immunogen is: Synthetic peptide, corresponding to amino acids 99-117 of Human RAIDD.
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
caspase and RIP adaptor with death domain; death adaptor molecule RAIDD; death domain containing protein CRADD; MGC9163; RAIDD; RIP-associated ICH1/CED3-homologous protein with death domain
CRADD; MRT34; RAIDD