|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, corresponding to amino acids 99-117 of Human RAIDD.|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
PA1-30806 detects RAIDD from human samples.
PA1-30806 has been successfully used in Western blot applications.
The PA1-30806 immunogen is: Synthetic peptide, corresponding to amino acids 99-117 of Human RAIDD.
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Caspase and RIP adapter with death domain; caspase and RIP adaptor with death domain; death adaptor molecule RAIDD; death domain containing protein CRADD; Death domain-containing protein CRADD; MGC9163; RAIDD; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain
Gene Aliases: CRADD; MRT34; RAIDD
UniProt ID: (Human) P78560
Entrez Gene ID: (Human) 8738
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