Immunogen sequence: MAAQGEPQVQ FKLVLVGDGG EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG QVTDQVEVNA QNSVPDEEAK TTTTNTQVEG DDEAAFLERL ARREERRQKR LQEALERQKE FDPTITDASL SLPSRRMQND TAENETTEKE EKSESRQERY EIEETETVTK SYQKNDWRDA EENKKEDKEK EEEEEEKPKR GSIGENQIKD EKIKKDKEPK EEVKSFMDRK KGFTEVKSQN; Positive Samples: NIH/3T3, COS-1, COS-7, Jurkat, 293T, Mouse testis, rat testis, C6, mouse kidney; Cellular Location: Cytoplasm, Melanosome, Nucleus, Nucleus envelope
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
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Protein Aliases: Androgen receptor-associated protein 24; GTP-binding nuclear protein Ran; GTPase Ran; guanosine triphosphatase Ran; member RAS oncogene family; OK/SW-cl.81; RanGTPase; Ras-like protein TC4; Ras-related nuclear protein
Gene Aliases: ARA24; Gsp1; OK/SW-cl.81; RAN; Rasl2-8; TC4