Proteintech

RANGRF Polyclonal Antibody

View all (5) RANGRF antibodies

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Datasheet

Protocols

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RANGRF Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of HepG2 cells using 10552-1-AP (RANGRF antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RANGRF Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 10552-1-AP ( RANGRF Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RANGRF Antibody in Western Blot (WB) — Mouse testis tissue were subjected to SDS PAGE followed by western blot with 10552-1-AP (RANGRF antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

10552-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:500	-
Immunocytochemistry (ICC/IF)	1:10-1:100	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RANGRF Fusion Protein Ag0824 (1-165 aa encoded by BC006486) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.27 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MEPTRDCPL FGGAFSAILP MGAIDVSDLR PVPDNQEVFC HPVTDQSLIV ELLELQAHVR GEAAARYHFE DVGGVQGARA VHVESVQPLS LENLALRGRC QEAWVLSGKQ QIAKENQQVR ARECVMSWKG GSGDAEIQVS ILTLIPLGSK GRDTSSGLAE AAPVPD (1-165 aa encoded by B C006486)

Target Information

May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MOG1 homolog; Ran guanine nucleotide release factor; Ran-binding protein MOG1; RanGNRF

Gene Aliases: 2400006H24Rik; HSPC165; HSPC236; MDS5; MOG1; RANGNRF; RANGRF

UniProt ID: (Human) Q9HD47, (Mouse) Q9JIB0

Entrez Gene ID: (Human) 29098, (Mouse) 57785

Function(s)

regulation of heart rate regulation of membrane depolarization ER to Golgi vesicle-mediated transport protein exit from endoplasmic reticulum regulation of membrane potential positive regulation of GTPase activity positive regulation of establishment of protein localization to plasma membrane regulation of membrane depolarization during cardiac muscle cell action potential regulation of sodium ion transmembrane transport positive regulation of protein localization to cell surface regulation of sodium ion transmembrane transporter activity transport nucleocytoplasmic transport protein transport

Process(es)

guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity Ran GTPase binding protein transporter activity sodium channel regulator activity ion channel binding

RANGRF Polyclonal Antibody

Product Details

10552-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

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