The synthetic peptide sequence is LLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQ
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Receptor Activator of Nuclear Factor kappa B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. It is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, this gene is mapped to 18q22.1.
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Protein Aliases: CD265; loss of heterozygosity, 18, chromosomal region 1; ODFR; Osteoclast differentiation factor receptor; Paget disease of bone 2; RANK; receptor activator of NF-kappaB; Receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; TNFRSF11A; Tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Aliases: CD265; FEO; LOH18CR1; Ly109; mRANK; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; RGD1563614; TNFRSF11A; TRANCE-R; TRANCER