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Proteintech
RAP1B Polyclonal Antibody
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Product Details
10840-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAP1B Fusion Protein Ag1282 (1-184 aa encoded by BC000176)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MREYKLVVL GSGGVGKSAL TVQFVQGIFV EKYDPTIEDS YRKQVEVDAQ QCMLEILDTA GTEQFTAMRD LYMKNGQGFA LVYSITAQST FNDLQDLREQ ILRVKDTDDV PMILVGNKCD LEDERVVGKE QGQNLARQWN NCAFLESSAK SKINVNEIFY DLVRQINRKT PVPGKARKKS SCQLL (1-184 aa encoded by BC000176)
Target Information
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GTP-binding protein smg p21B; Ras family small GTP binding protein RAP1B; RAS related protein 1b; Ras-related protein Rap-1b; RAS-related protein RAP1B; small GTP binding protein
Gene Aliases: 2810443E11Rik; K-REV; OK/SW-cl.11; RAL1B; RAP1B
UniProt ID: (Human) B4DW74, (Rat) Q62636, (Mouse) Q99JI6
Entrez Gene ID: (Human) 5908, (Rat) 171337, (Mouse) 215449
microvillus assembly
Rap protein signal transduction
establishment of endothelial barrier
cellular response to cAMP
regulation of cell junction assembly
regulation of establishment of cell polarity
small GTPase mediated signal transduction
metabolic process
cell proliferation
negative regulation of calcium ion-dependent exocytosis
positive regulation of ERK1 and ERK2 cascade
negative regulation of synaptic vesicle exocytosis
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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