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Invitrogen
RAP2B Polyclonal Antibody
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Product Details
PA5-30144
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RAP2B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A431, H1299, HepG2, mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Xenopus laevis (96%), Pig (100%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ras-related protein Rap-2b; small GTP binding protein; unnamed protein product
Gene Aliases: 4021402C18Rik; AA408554; RAP2B
UniProt ID: (Human) P61225, (Mouse) P61226
Entrez Gene ID: (Human) 5912, (Mouse) 74012
signal transduction
platelet activation
negative regulation of cell migration
Rap protein signal transduction
regulation of protein tyrosine kinase activity
platelet aggregation
establishment of endothelial intestinal barrier
small GTPase mediated signal transduction
positive regulation of protein autophosphorylation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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