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Product Details
PA5-110270
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:200-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RAPH1 (NP_998754.1). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.73 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2855681 |
Product Specific Information
Sequence of this protein is as follows: MEQLSDEEID HGAEEDSDKE DQDLDKMFGA WLGELDKLTQ SLDSDKPMEP VKRSPLRQET NMANFSYRFS IYNLNEALNQ GETVDLDALM ADLCSIEQEL SSIGSGNSKR QITETKATQK LPVSRHTLKH GTLKGLSSSS NRIAKPSHAS YSLDDVTAQL EQASLSMDEA AQQSVLEDTK PLVTNQHRRT ASAGTVSDAE VHSISNSSHS SITSAASSMD SLDIDKVTRP QELDLTHQGQ
Target Information
This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein; Lamellipodin; PREL-2; Proline-rich EVH1 ligand 2; Protein RMO1; RAPH1; Ras-associated and pleckstrin homology domains-containing protein 1
Gene Aliases: 9430025M21Rik; ALS2CR18; ALS2CR9; C730009O10Rik; KIAA1681; LPD; PREL-2; PREL2; RalGDS/AF-6; RAPH1; RMO1
UniProt ID: (Human) Q70E73
Entrez Gene ID: (Human) 65059, (Rat) 363239, (Mouse) 77300
Molecular Function:
scaffold/adaptor protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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