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Product Details
PA5-115824
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RAPSN(Accession Q13702), corresponding to amino acid residues E372-V412.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900458
Product Specific Information
Antibody detects endogenous levels of total Rapsyn.
Target Information
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 43 kDa postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa acetylcholine receptor-associated protein; Acetylcholine receptor-associated 43 kDa protein; CMS1D; CMS1E; MGC3597; RAPsyn; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; RING finger protein 205
Gene Aliases: 43kDa; CMS11; CMS4C; FADS; Nraps; Raps; RAPSN; RAPSYN; RNF205
UniProt ID: (Human) Q13702, (Mouse) P12672
Entrez Gene ID: (Human) 5913, (Rat) 362161, (Mouse) 19400
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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