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Proteintech
RASA4B Polyclonal Antibody
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Product Details
31288-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RASA4B fusion protein Ag35038
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: KVSINNTGLL GSYHPGVFRG DKWSCCHQKE KTGQGCDKTR SRVTLQEWND PLDHDLEAQL IYRHLLGVEA MLWERHRELS GGAEAGTVPT SPGKVPEDSL ARLLRVLQDL REAHSSSPAG SPPSEPNCLL ELQT
Target Information
RASA4B (RAS p21 protein activator 4B) is a gene encoding a protein that functions as a GTPase-activating protein (GAP) for the Ras family of proteins, which are critical regulators of cell proliferation, differentiation, and survival. Located on chromosome 7q22.1, the RASA4B gene product is involved in the inactivation of Ras by stimulating the hydrolysis of Ras-bound GTP to GDP, thus acting as a molecular switch. The structure of RASA4B includes conserved domains for catalytic activity, such as the RasGAP domain, which is essential for its interaction with Ras. Dysregulation or mutations in RASA4B can lead to aberrant Ras signaling, contributing to oncogenesis and other pathologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: putative Ras GTPase-activating protein 4B
Entrez Gene ID: (Human) 100271927
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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