Recommended positive controls: 293T, A431.
Predicted reactivity: Mouse (98%), Rat (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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Protein Aliases: Ras GTPase-activating protein nGAP; Ras protein activator like 1; RAS protein activator-like 2
Gene Aliases: NGAP; RASAL2
UniProt ID: (Human) Q9UJF2
Entrez Gene ID: (Human) 9462
Molecular Function: GTPase-activating protein