Immunogen sequence: LSVLHSLLWE VVSQLDKATV AKLGPLPRVL ADITKSLTNP TPIQQQLRRF TEHNSSPNVS GSLSSGLQKI FEDPT
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 97%.
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ras GTPase-activating protein nGAP; Ras protein activator like 1; RAS protein activator-like 2
Gene Aliases: 6530401P13; A330066M24Rik; NGAP; RASAL2
UniProt ID: (Human) Q9UJF2
Molecular Function: GTPase-activating protein