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Invitrogen
RASSF2 Polyclonal Antibody
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FIGURE: 1 / 1
RASSF2 Antibody (PA5-90687) in WB
Western blot analysis of RASSF2 in extracts of Raji cells. Samples were incubated with RASSF2 Polyclonal antibody (Product # PA5-90687) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 1s.
Product Details
PA5-90687
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_0555521)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MQDDNERIRP PPSSSSWHSG CNLGAQGTTL KPLTVPKVQI SEVDAPPEGD QMPSSTDSRG LKPLQEDTPQ LMRTRSDVGV RRRGNVRTPS D; Positive Samples: Raji; Cellular Location: Cytoplasm, Nucleus
Target Information
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centromere protein 34; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain-containing protein 2; RP4-599I11.1
Gene Aliases: CENP-34; KIAA0168; RASFADIN; RASSF2
UniProt ID: (Human) P50749
Entrez Gene ID: (Human) 9770
skeletal system development
ossification
protein phosphorylation
cell cycle
positive regulation of protein autophosphorylation
negative regulation of peptidyl-serine phosphorylation
epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade
positive regulation of apoptotic process
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein kinase activity
positive regulation of JNK cascade
bone remodeling
homeostasis of number of cells
protein stabilization
negative regulation of NIK/NF-kappaB signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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