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Proteintech
RB1 Polyclonal Antibody
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Product Details
25628-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RB1 Fusion Protein Ag22578 (373-581 aa encoded by BC039060)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TPVRTVMNT IQQLMMILNS ASDQPSENLI SYFNNCTVNP KESILKRVKD IGYIFKEKFA KAVGQGCVEI GSQRYKLGVR LYYRVMESML KSEEERLSIQ NFSKLLNDNI FHMSLLACAL EVVMATYSRS TSQNLDSGTD LSFPWILNVL NLKAFDFYKV IESFIKAEGN LTREMIKHLE RCEHRIMESL AWLSDSPLFD LIKQSKDREG (373-581 aa encoded by BC039060)
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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