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Invitrogen
RBFOX2 Polyclonal Antibody
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Product Details
PA5-113686
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N terminal region of human RBM9 (aa 74-123).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: STQAHGEQSS NSPSTQNGSL TTEGGAQTDG QQSQTQSSEN SESKSTPKRL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Target Information
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fox-1 homolog B; fox-1 homologue; Hexaribonucleotide-binding protein 2; Repressor of tamoxifen transcriptional activity; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA-binding motif protein 9; RNA-binding protein 9
Gene Aliases: dJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBFOX2; RBM9; RTA
UniProt ID: (Human) O43251
Entrez Gene ID: (Human) 23543
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
nervous system development
RNA splicing
fibroblast growth factor receptor signaling pathway
regulation of definitive erythrocyte differentiation
RNA metabolic process
radial glia guided migration of Purkinje cell
intracellular estrogen receptor signaling pathway
regulation of cell proliferation
negative regulation of transcription, DNA-templated
dendrite morphogenesis
neuromuscular process controlling balance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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