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Product Details
PA5-40331
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1.4 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
4-8 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide directed towards the N-terminal of human RBM10 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 2% sucrose |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2608208 |
Product Specific Information
Peptide sequence: QRRRRRRHRH SPTGPPGFPR DGDYRDQDYR TEQGEEEEEE EDEEEEEKAS
Sequence homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
The protein encoded by this gene contains RNA recognition motif found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regulation of alternative splicing, and protein components of snRNPs. In vitro studies showed that the rat homolog bound to RNA homopolymers, with a preference for G and U polyribonucleotides. This gene is part of a gene cluster on chromosome Xp11.23, and its 3' end lies within 20 kb upstream of UBE1. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G patch domain-containing protein 9; rna-binding; RNA-binding motif protein 10; RNA-binding protein 10; RNA-binding protein S1-1; S1-1
Gene Aliases: DXS8237E; E430039K10Rik; GPATC9; GPATCH9; KIAA0122; RBM10; S1-1; TARPS; ZRANB5
UniProt ID: (Human) P98175, (Mouse) Q99KG3
Entrez Gene ID: (Human) 8241, (Mouse) 236732
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
biological_process
RNA splicing
regulation of apoptotic process
negative regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
regulation of smooth muscle cell apoptotic process
positive regulation of smooth muscle cell apoptotic process
negative regulation of mRNA splicing, via spliceosome
3'-UTR-mediated mRNA stabilization
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