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Invitrogen
RBM10 Polyclonal Antibody
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Product Details
PA5-83253
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RBM10. Recombinant protein control fragment (Product #RP-95471).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MEYERRGGRG DRTGRYGATD RSQDDGGENR SRDHDYRDMD YRSYPREYGS QEGKHDYDDS SEEQSAEDSY EASPGSETQR R
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 98%.
Target Information
The protein encoded by this gene contains RNA recognition motif found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regulation of alternative splicing, and protein components of snRNPs. In vitro studies showed that the rat homolog bound to RNA homopolymers, with a preference for G and U polyribonucleotides. This gene is part of a gene cluster on chromosome Xp11.23, and its 3' end lies within 20 kb upstream of UBE1. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; G patch domain-containing protein 9; G-patch domain containing 9; KIAA0122; rna-binding; RNA-binding motif protein 10; RNA-binding protein 10; RNA-binding protein S1-1; S1-1; unnamed protein product; zinc finger RANBP2-type containing 5
Gene Aliases: DXS8237E; GPATC9; GPATCH9; KIAA0122; MINAS-60; RBM10; S1-1; TARPS; ZRANB5
UniProt ID: (Human) P98175
Entrez Gene ID: (Human) 8241
negative regulation of transcription from RNA polymerase II promoter
mRNA splicing, via spliceosome
mRNA processing
negative regulation of cell proliferation
RNA splicing
negative regulation of mRNA splicing, via spliceosome
3'-UTR-mediated mRNA stabilization
negative regulation of vascular smooth muscle cell proliferation
vascular associated smooth muscle cell apoptotic process
regulation of vascular associated smooth muscle cell apoptotic process
positive regulation of vascular associated smooth muscle cell apoptotic process
vascular associated smooth muscle cell proliferation
negative regulation of ribosomal large subunit export from nucleus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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