Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
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Protein Aliases: Paraspeckle protein 2; PSP2; rna-binding; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; Synaptotagmin-interacting protein; SYT-interacting protein; transmembrane protein 137
Gene Aliases: COAA; PSP2; RBM14; SIP; SYTIP1; TMEM137
UniProt ID: (Human) Q96PK6
Entrez Gene ID: (Human) 10432