May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
Protein Aliases: one twenty two protein; one twenty-two; One-twenty two protein 1; putative RNA-binding protein 15; RNA binding motif protein 15; RNA-binding motif protein 15; RNA-binding protein 15
Gene Aliases: C230088J01Rik; Kiaa4257; mKIAA1438; OTT; OTT1; RBM15; SPEN