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Product Details
PA5-65572
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human RBM15. Recombinant protein control fragment (Product #RP-104879).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664499
Product Specific Information
Immunogen sequence: RGARDRTPPLL YRDRDRDLYP DSDWVPPPPP VRERSTRTAA TSVPAYEPLD SLDRRRDGWS LDRDRGDRDL PSSRDQPRKR RLPEESGGRH LDRSPESDRP RKRHC
Highest antigen sequence identity to the following orthologs - mouse 91%, rat 93%.
Target Information
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: one twenty two protein; one twenty-two; One-twenty two protein 1; RNA-binding motif protein 15; RNA-binding protein 15
Gene Aliases: OTT; OTT1; RBM15; SPEN
UniProt ID: (Human) Q96T37
Entrez Gene ID: (Human) 64783
mRNA splicing, via spliceosome
patterning of blood vessels
positive regulation of transcription of Notch receptor target
viral process
negative regulation of myeloid cell differentiation
negative regulation of transcription, DNA-templated
spleen development
ventricular septum morphogenesis
placenta blood vessel development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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