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Invitrogen
RBM41 Polyclonal Antibody
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Product Details
PA5-60155
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RBM41. Recombinant protein control fragment (Product #RP-92118).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SDEHVLEELE TEGERQLKSL LQHQLDTSVS IEECMSKKES FAPGTMYKPF GKEAAGTMTL SQFQTLHEKD QETASLRELG LNETEILIWK SHVSGEKKTK LRATPEAIQN RLQDIEERIS ERQRILCLPQ RFAKSKQLTR REMEI
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.
Target Information
RBM41, known as RNA Binding Motif Protein 41, is identified as a novel component of the minor spliceosome, particularly interacting with its paralog, U11/U12-65K. Both RBM41 and U11/U12-65K share similar C-terminal RNA recognition motifs (RRMs), which are crucial for their role in spliceosomal activity. Distinctly, RBM41 has been associated with spliceosomal functions, although its precise cellular functions remain largely unexplored. Understanding the structural and functional parallels between RBM41 and U11/U12-65K aids in elucidating the mechanisms underlying minor spliceosome activity. The minor spliceosome itself is involved in the splicing of U12-type introns, thus playing a significant role in the regulation of gene expression. Additionally, RBM41's functional characterization in protein complexes and its involvement with RNA-binding activities enrich our understanding of gene regulation and cellular processes where the spliceosome plays a pivotal role. Research on RBM41 contributes to broader insights into RNA splicing and molecular genetics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNA-binding motif protein 41; RNA-binding protein 41
Gene Aliases: RBM41
UniProt ID: (Human) Q96IZ5
Entrez Gene ID: (Human) 55285
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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