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Bethyl Laboratories
RBM8a Polyclonal Antibody
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FIGURE: 1 / 1
RBM8a Antibody (A301-033A) in WB
Detection of human and mouse RBM8a by western blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg), HEK293T (T; 50 µg), and mouse NIH 3T3 (M; 50 µg) cells. Antibody: Affinity purified rabbit anti-RBM8a antibody (Product # A301-033A) used for WB at 0.04 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A301-033A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of Human RNA binding motif protein 8A.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, X. laevis, X. tropicalis and Bovine
Target Information
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Binder of OVCA1-1; BOV-1; BOV1; BOV1A; BOV1B; BOV1C; ribonucleoprotein RBM8; Ribonucleoprotein RBM8A; RNA binding motif protein 8B; rna-binding; RNA-binding motif protein 8A; RNA-binding protein 8A; RNA-binding protein Y14
Gene Aliases: 2310057C03Rik; AA673428; BOV-1A; BOV-1B; BOV-1C; C1DELq21.1; DEL1q21.1; HSPC114; MDS014; RBM8; RBM8A; RBM8B; TAR; Y14; ZNRP; ZRNP1
UniProt ID: (Human) Q9Y5S9, (Mouse) Q9CWZ3
Entrez Gene ID: (Human) 9939, (Mouse) 60365
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
regulation of translation
mRNA 3'-end processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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