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Invitrogen
RBMX Polyclonal Antibody
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FIGURE: 1 / 7
RBMX Antibody (PA5-99433) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded RBMX in human Breast tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with RBMX polyclonal antibody (Product # PA5-99433) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-99433
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
C. elegans,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RBMX(Accession P38159), corresponding to amino acid residues N20-N70.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total hnRNP G.
Target Information
hnRNP G is a glycoprotein, which was originally identified as an autoantigen from German shepherd dogs with lupus-like syndrome. The gene encoding hnRNP G is located on chromosome Xq26 and is ubiquitously expressed. It contains one RNP-consensus RNA binding domain (RBD) and is related to RBMY, which is involved in spermatogenesis, and hnRNP G-T, which is a testis specific protein. All three proteins interact with Tra2b and therefore, are involved in pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Glycoprotein p43; Heterogeneous nuclear ribonucleoprotein G; hnRNP G; RNA binding motif protein, X chromosome; RNA-binding motif protein, X chromosome; RNA-binding motif protein, X chromosome retrogene; RNA-binding motif protein, X chromosome retrogene-like
Gene Aliases: hnRNP G; hnRNP-G; HNRNPG; HNRPG; MRXS11; RBMX; RBMXP1; RBMXRT; RNMX
UniProt ID: (Human) P38159, (Mouse) Q9WV02, (Rat) Q4V898
Entrez Gene ID: (Human) 27316, (Mouse) 19655, (Rat) 302855
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
osteoblast differentiation
transcription from RNA polymerase II promoter
membrane protein ectodomain proteolysis
gene expression
positive regulation of transcription from RNA polymerase II promoter
negative regulation of mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome
protein homooligomerization
cellular response to interleukin-1
transcription, DNA-templated
mRNA splice site selection
mRNA processing
RNA splicing
positive regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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