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Proteintech
RBP3 Polyclonal Antibody
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Product Details
14352-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RBP3 Fusion Protein Ag5699 (898-1247 aa encoded by BC039844)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AMSATTGKA WDLAGVEPDI TVPMSEALSI AQDIVALRAK VPTVLQTAGK LVADNYASAE LGAKMATKLS GLQSRYSRVT SEVALAEILG ADLQMLSGDP HLKAAHIPEN AKDRIPGIVP MQIPSPEVFE ELIKFSFHTN VLEDNIGYLR FDMFGDGELL TQVSRLLVEH IWKKIMHTDA MIIDMRFNIG GPTSSIPILC SYFFDEGPPV LLDKIYSRPD DSVSELWTHA QVVGERYGSK KSMVILTSSV TAGTAEEFTY IMKRLGRALV IGEVTSGGCQ PPQTYHVDDT NLYLTIPTAR SVGASDGSSW EGVGVTPHVV VPAEEALARA KEMLQHNQLR VKRSPGLQDH L (898-1247 aa encoded by BC039844)
Target Information
Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: interphotoreceptor retinoid binding protein; Interphotoreceptor retinoid-binding protein; interphotoreceptor retinol- binding protein; interstitial retinol binding protein 3; Interstitial retinol-binding protein; IRBP; IRBP precursor; retinol binding protein 3, interstitial; Retinol-binding protein 3
Gene Aliases: D10S64; D10S65; D10S66; IRBP; Rbp-3; RBP3; RBPI; RP66
UniProt ID: (Human) P10745, (Mouse) P49194
Entrez Gene ID: (Human) 5949, (Rat) 24711, (Mouse) 19661
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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