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Invitrogen
RBP3 Polyclonal Antibody
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Product Details
PA5-65293
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human RBP3. Recombinant protein control fragment (Product #RP-106004).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GVEPDITVPMS EALSIAQDIV ALRAKVPTVL QTAGKLVADN YASAELGAKM ATKLSGLQSR YSRVTSEVAL AEILGADLQM LSGDPHLKAA HIPENAKDR
Highest antigen sequence identity to the following orthologs - mouse 90%, rat 92%.
Target Information
Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Interphotoreceptor retinoid-binding protein; interstitial retinol binding protein 3; Interstitial retinol-binding protein; IRBP; IRBP precursor; retinol binding protein 3, interstitial; Retinol-binding protein 3
Gene Aliases: D10S64; D10S65; D10S66; IRBP; RBP3; RBPI; RP66
UniProt ID: (Human) P10745
Entrez Gene ID: (Human) 5949
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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