This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human RBP4/PRBP.
Retinal binding protein (RBP4) belongs to the lipocalin superfamily of proteins. It is synthesized and secreted by hepatic paraenchymal cells and is involved in the binding of retinol and transthyretin preventing loss by glomerular filtration and renal excretion before transport to the peripheral tissues. Increased plasma levels of retinal binding protein have been shown to cause systemic insulin resistance and as such, the protein may play a role in the pathogenesis of Type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Plasma retinol-binding protein; Plasma retinol-binding protein(1-176); Plasma retinol-binding protein(1-179); Plasma retinol-binding protein(1-181); Plasma retinol-binding protein(1-182); PRBP; RBP; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial
Gene Aliases: MCOPCB10; PRO2222; RBP4; RDCCAS
UniProt ID: (Human) P02753
Entrez Gene ID: (Human) 5950
Molecular Function: transfer/carrier protein