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Invitrogen
RBP4 Polyclonal Antibody
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FIGURE: 1 / 1
RBP4 Antibody (PA5-90882) in WB
Western blot analysis of RBP4 in extracts of various cell lines. Samples were incubated with RBP4 Polyclonal antibody (Product # PA5-90882) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-90882
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human RBP4 (NP_0067352)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Amount
45 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ERDCRVSSFR VKENFDKARF SGTWYAMAKK DPEGLFLQDN IVAEFSVDET GQMSATAKGR VRLLNNWDVC ADMVGTFTDT EDPAKFKMKY WGVASFLQKG NDDHWIVDTD YDTYAVQYSC RLLNLDGTCA DSYSFVFSRD PNGLPPEAQK IVRQRQEELC LARQYRLIVH NGYCDGRSER NLL; Positive Samples: SW620, HeLa, OVCAR3, Mouse liver, Mouse spleen
Target Information
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, cellular; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial; unnamed protein product
Gene Aliases: MCOPCB10; PRO2222; Rbp-4; RBP4; RDCCAS
UniProt ID: (Human) P02753, (Mouse) Q00724
Entrez Gene ID: (Human) 5950, (Mouse) 19662
retinoid metabolic process
eye development
positive regulation of immunoglobulin production
gluconeogenesis
spermatogenesis
heart development
visual perception
phototransduction, visible light
male gonad development
response to xenobiotic stimulus
response to muscle activity
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
response to insulin
retinol transport
retinol metabolic process
retinal metabolic process
glucose homeostasis
response to ethanol
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
detection of light stimulus involved in visual perception
retina development in camera-type eye
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
vitamin A import
transport
embryo development
positive regulation of immunoglobulin secretion
vitamin transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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